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January 2015

Volume 1  Issue 1 

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Case Report

Topical Clobetasol in Combination with Tretinoin for Prevention of Scar Formation After Superficial Skin Burn

Arash Taheri MD, Parisa Mansoori MD, Laura Sandoval DO, and Steven R Feldman

 Superficial second degree skin burns can heal with or without resulting scar. Scar formation occurs when inflammation remains in the dermis after re-epithelialization, contributing to changes in skin architecture. Suppression of inflammation and fibroblast activity using topical corticosteroids immediately after re-epithelialization may prevent scar formation.Additionally, tretinoin can increase trans-epidermal absorption and efficacy of topical corticosteroids.                                                                                                      

                                                                                                                                                                                      Download PDF   Full text       ______________________________________________________________________________________________

Case Report
Ant-Induced Alopecia, A Case Series

Parisa Mansoori, Laura F. Sandoval DO, Arash Taheri, and Omar P Sangueza

Ants can cut hairs and cause localized hair shedding without affecting the structure of hair follicles. Pheidole pallidula can cut the hairs just above the skin surface and cause hair shedding resembling alopecia. There are several reports of antinduced alopecia in medical literature, all of which have been from Iran or Turkey and caused by P. pallidula. This species of ant is also found in many European countries of the Mediterranean region, North Africa, and the US, and therefore, this diagnosis should be considered in cases of localized alopecia or hair shedding in these geographic areas.                                                                                                      

                                                                                                                                                                                          Download PDF  Full text   ______________________________________________________________________________________________

Case Report
Granular Parakeratosis – Case Report

Rogério Nabor Kondo*, Rubens Pontello Junior, Renata Maria Pontello, Rodrigo Almeida de Medeiros

A 28-year old woman is having 4 months of hyper pigmented and hyper keratotic plaques associated with discrete pruritus,in the inguinal folds. Histological examination displayed parakeratosis and retention of multiple basophilic granules in the stratum corneum. Diagnosis of granular parakeratosis was confirmed after clinic-histological correlation.                                                                                

                                                                                                                                                                                               Download PDF  Full text ______________________________________________________________________________________________

Research Article

Eradication of Multiple Primary and Metastatic Melanoma Types in Vitro by Human Recombinant Dnase1

Karli Rosner*, Evangelia Kirou, Darius R. Mehregan, Judith Abrams, Seongho Kim and Tal Rosner

To address treatment-resistant metastatic melanoma, we previously engineered a form of human recombinant deoxyribonuclease-1 (hrDNase) with a demonstrated killing efficiency of 70-100% in the Mel-Juso human melanoma cell line. hrDNase1 was previously shown to eliminate Mel-Juso cells, an apoptosis-resistant cell line, through a mechanism that resembles apoptosis.                                                                                                  

                                                                                                                                                                                       Download PDF  Full text ______________________________________________________________________________________________

Research Article

Preservatives in a Selection of Consumer Products Purchased in the United Arab Emirates
Fatima Al Mamari*, Cecilia Svedman, Lena Persson, Malin Engfeldt

In both Europe and the USA it is mandatory that personal care products are labelled with an ingredient list. This facilitates the possibility to assess exposure to known contact allergens. However, if the products are incorrectly labelled it might pose an obstacle for patients trying to avoid allergens and obstruct the evaluation ofclinical relevance for the clinician.                                                                                                

                                                                                                                                                                                           Download PDF  Full text

 

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